JuniperPublishers- Spermatogonial Stem Cell Technology and Regenerative Medicine
Journal of Surgery - JuniperPublishers Abstract The biologic activities of spermatogonial stem cells (SSCs) are the base for spermatogenesis and thus sustained male fertility. Therefore, comprehending the mechanisms governing their ability to both self‐ renew and differentiate is necessary. Moreover, because SSCs are the just adult stem cell to contribute genetic information to the next generation, they are a good target for genetic change. Some researchers have reported the derivation of multipotent cells from mouse and human spermatogonial stem cells. These spermatogonial stem cells demonstrate similarities with embryonic stem cells for phenotype and functionality, showing that these cells may be a promising alternative origin for stem-cell based therapies in regenerative medicine. Keywords: Spermatogonial stem cell; Regenerative medicine; Transplantation Go to Introduction Spermatogonial stem cell Germ cell development begins with the characteristics o...