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The Budding Scavenger-Juvenile Xanthogranuloma

  Abstract Juvenile xanthogranuloma is an uncommon, proliferative, non-Langerhans histiocytic cell disorder arising from dendrocytes. Juvenile xanthogranuloma is commonly discerned in childhood and demonstrates a male predominance. Of obscure aetiology, juvenile xanthogranuloma appears as a consequence of a hitherto uncharted infectious or physical stimulus which engenders a granulomatous histiocytic response. Typically, juvenile xanthogranuloma represents as an asymptomatic, solitary or multiple, firm, yellow, orange or brown papule or nodule. Cutaneous lesions demonstrate an intense infiltration of histiocytic cells within the superficial dermis. Histiocytic cells are intermingled with mature lymphocytes, plasma cells and eosinophils. Also, foam cells, foreign body giant cells and Touton giant cells emerge within mature lesions. Immune reactivity to CD68, vimentin, alpha-1 antichymotrypsin, lysozyme, Factor XIIIa, macrophage inflammatory protein (Ki-MIP) and anti-CD
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Obesity and Gut Microbiota

  Abstract The prevalence of overweight and obesity among children and adolescents has risen dramatically increasing and is considered a high-income country problem. Different trials surgical and medical have been tried over years. Recently, the link of gut microbiota to overweight and obesity has been documented in many literatures. In our mini review we will explore this relation ship Read more about this article:  https://juniperpublishers.com/oajs/OAJS.MS.ID.555862.php Read more   Juniper Publishers Google Scholar  articles :  https://scholar.google.com/citations?view_op=view_citation&hl=en&user=sLK6eBEAAAAJ&citation_for_view=sLK6eBEAAAAJ:ZHo1McVdvXMC
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Description of Surgery Technique of The Lower Trapezius Transfer with Semitendinosus and Gracilis Tendon Graft for The Treatment of Massive or Irreparable Rotator Cuff Tear

Abstract Background: The current work describes a surgery technique where the autograft of hamstring tendon (semitendinosus and gracilis) was used as adjuvant in the transfer of the lower trapezius for the treatment of massive or irreparable rotator cuff tear. There is a theoretical advantage that the graft takes a greater footprint area in the greater tuberosity of the humerus corresponding to the infraspinatus, thus recreating the native anatomy more accurately. Methods: The autograft of hamstring tendon was attached to the lower trapezius through an incision of 4cm in the middle third of the scapular spine and transferred to the footprint of the infraspinatus in the greater tuberosity of the humerus, where it is attached through the second incision under the lateral acromial margin. Result: The patient was examined preoperatively and after 6 months of follow-up, and his pain, according to the Visual Analogue Scale, varied from 8 to 3, the range of motion improved
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Happy Easter- Juniper Publishers

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  Easter Wishes - Juniper Publishers
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Qualitative Approach to Understanding Barriers to Delivering Difficult News in Sub Saharan Africa- Juniper Publishers

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  Journal of Surgery -  JuniperPublishers Dear Editor, Communication, especially delivery of difficult news (DDN), remains a key part of clinical practice. Despite its importance, many medical providers lack the skill and ability to effectively DDN to their patients. Due to lack of data specific to sub-Saharan Africa and to help us develop an appropriate training tool for this geographical area, we sought to explore what challenges and barriers residents at our institution faced when they deliver difficult news to their patients. Methodology A qualitative approach using thematic analysis was adopted and a self-administered open ended survey was administered amongst residents currently doing their Masters in Medicine at the Aga Khan University Hospital in Nairobi and Dar es Salaam. The survey was emailed to all the residents within the two campuses using the REDCap software. Two independent researchers identified recurring th
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Paramedic Student Progress in Medication Calculation- Juniper publishers

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  Journal of Surgery -  JuniperPublishers Emergency Medical Service (EMS) is one of the health professions that society requires. EMS involves the use of certain emergency medications to save lives. Therefore, EMS providers (paramedic) should acquire sufficient training in medication administration. A part of the training focuses on the knowledge of medications, indications for use, contraindications (side effects), and dosing skills considering the type of disease, concentration of medication, age, or weight of the patient. A student who is trained to be a paramedic should be adequately skilled to properly calculate the dosage of medications. This study aims to determine the paramedic students’ ability and its progress in medication calculation while studying in EMS program in Prince Sultan Bin Abdulaziz College for EMS (PSCEMS), King Saud University (KSU), Riyadh, Saudi Arabia. Literature Review A few research articles wer
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The Clinical Outcomes Regarding to Tumor-Infıltrating Lymphocytes in the Breast Cancer Patients Treated with Neoadjuvant Chemotherapy- Juniper Publishers

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  Journal of Surgery -  JuniperPublishers  In breast cancer great endeavors are going on to find new markers in determining the prognosis. In addition to well-known prognostic factors such as tumour size, grade, nodal status, molecular subtype, proliferation index, gene-expression based recurrence score, recently there is increasing evidence that tumor-infiltrating lymphocytes (TILs) are of important role as an immune biomarker in breast carcinoma [1-3]. TILs might be a reflection of host immune response which plays an important role in cancer control and patient’s clinical outcome. TILs are mononuclear immune cells that infiltrate tumour tissue and mainly comprised of cytotoxic (CD8+) T cells as well as macrophages, helper (CD4+) T cells, B cells, and NK cells [4,5]. There are two types of TILs: Stromal TILs (sTILs) are defined as the percentage of tumour stromal field in which lymphocytes are located without direct connection to tumour cells. In contrast, intratumoural T
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